| Sun 27-Nov-2022 |
|---|
| 14:00 | Portsmouth Women | 7‑0 | Bowers & Pitsea Ladies | |
| 14:00 | Redcar Town Ladies | 2‑7 | Leeds Women | |
| 14:00 | Sporting Khalsa W | 1‑2 | Peterborough W | |
| 14:00 | Wem Town Women | 1‑5 | Nott'm Forest Women | |
| 14:00 | Wolverhampton Women | 5‑0 | Northampton Town Ladies | |
| 13:00 | AFC Fylde Women | 4‑5 | Middlesbrough Women | |
| 13:00 | Ashford United Ladies | 1‑3 | Actonians LFC | |
| 13:00 | Bournemouth Sports Ladies | 3‑2 | Torquay United Women | |
| 13:00 | Cardiff Women | 6‑0 | Keynsham Town W | |
| 13:00 | Cheadle Town Women | 0‑1 | Burnley Women | |
| 13:00 | Coventry Sphinx W | 1‑5 | Solihull Moors W | |
| 13:00 | Huddersfield Women | 3‑0 | Durham Cestria W | |
| 13:00 | Ipswich Women | 3‑0 | London Seaward | |
| 13:00 | Lichfield City Ladies | 0‑8 | West Brom Women | |
| 13:00 | Liverpool Feds Women | 4‑0 | Merseyrail Ladies | |
