The following are the top scorers in the Spanish Segunda B4 during the 2020-2021 season
- Alberto Quiles (Recreativo Huelva) - 8
- Pito Camacho (Linense) - 9
- Diego Cervero (Atletico Sanluqueno CF) - 6
- Eduardo Ubis (Algeciras) - 6
- Francis (CD San Fernando) - 6
- Juanmi Callejon (Marbella) - 5
- Ivan Turrillo (Algeciras) - 5
- Yaimil Medina (Recreativo Huelva) - 5
- Jonathan Quintero (Tamaraceite) - 4
- Seth Airam (Recreativo Huelva) - 4
- Jonathan Biabiany (CD San Fernando) - 4
- Manuel Nieto (Cadiz B) - 4
- Joel del Pino (Las Palmas Atletico) - 3
- Ivan Chapela (Cadiz B) - 3
- Chuli (Recreativo Huelva) - 3
- Jon Amelibia (CD San Fernando) - 3
- Andreu Arasa (Atletico Sanluqueno CF) - 3
- Jordi Tur (Cadiz B) - 3
- Rafael Tresaco (Marbella) - 3
- Kevin Bautista (Atletico Sanluqueno CF) - 3
