The following are the top scorers in the Spanish Segunda B4 during the 2020-2021 season
- Pito Camacho (Linense) - 6
- Alberto Quiles (Recreativo Huelva) - 8
- Francis (CD San Fernando) - 6
- Diego Cervero (Atletico Sanluqueno CF) - 6
- Juanmi Callejon (Marbella) - 5
- Jonathan Biabiany (CD San Fernando) - 4
- Seth Airam (Recreativo Huelva) - 4
- Ivan Turrillo (Algeciras) - 4
- Jonathan Quintero (Tamaraceite) - 3
- Jon Amelibia (CD San Fernando) - 3
- Chuli (Recreativo Huelva) - 3
- Manuel Nieto (Cadiz B) - 3
- Rafael Tresaco (Marbella) - 3
- Kevin Bautista (Atletico Sanluqueno CF) - 3
- Luis Alcalde (Linense) - 2
- Juan Serrano (Algeciras) - 2
- Jesus Sillero (Recreativo Huelva) - 2
- Andreu Arasa (Atletico Sanluqueno CF) - 2
- Javi Perez (Cadiz B) - 2
- Chumbi (Marbella) - 2
