The following are the top scorers in the Mexican Liga MX during the 2020-2021 season
- Jonathan Rodriguez (Cruz Azul) - 8
- Andre-Pierre Gignac (Tigres UANL) - 10
- Juan Dinenno (Pumas UNAM) - 10
- Dario Lezcano (FC Juarez) - 5
- Camilo (Mazatlan FC) - 8
- Angel Mena (Club Leon FC) - 7
- Henry Martin (Club America) - 7
- Hugo Silveira (Club Queretaro) - 6
- Nicolas Lopez (Tigres UANL) - 6
- Alexis Pedro Canelo (Toluca) - 6
- Santiago Ormeno (Puebla) - 6
- Federico Vinas (Club America) - 6
- Rogelio Funes Mori (Monterrey) - 6
- Jean Meneses (Club Leon FC) - 5
- Jose Macias (Guadalajara) - 5
- Carlos Gonzalez (Pumas UNAM) - 5
- Nicolas Sanchez (Monterrey) - 5
- Julio Cesar Furch (Santos Laguna) - 5
- Victor Davila (CF Pachuca) - 5
- Francisco Cordova (Club America) - 5
